Prof. Ellie Barnes
Ellie Barnes is Professor of Hepatology and Experimental Medicine, and an MRC Senior Clinical Fellow at Oxford University. She has spent many years working on the immune control of HCV in natural infection. More recently, she has been developing T cell vaccines against HCV using simian adeno and MVA viral vectors in prime-boost strategies, in collaboration with the industry. She is also developing vaccines designed to target multiple HCV genotypes. These approaches have generated durable, high-magnitude, polyfunctional T cells that target multiple HCV antigens in healthy volunteers. The efficacy of the first of these vaccines is currently being assessed in a phase-II study in intra-venous drug using populations in the USA.